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Questions, experiences and reviews (80)

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Atropine sulphate eye drops?
I was researching plants such as Datura and Deadly Nightshade recently, and noticed that atropine is used in eyedrops. Would Atropine sulphate be the same chemical as found in these plants? Is there a difference between Atropine and Atropine sulphate?
Scott S
06/20/09
Reply
How does atropine work?
When somebody is poisoned by TTX, doctors will give you atropine to resolve the bradycardia. But why does this work? i thought TTX block the sodium channels and atropine block the acetylcholine receptors. I don't get why atropine works. anyone?
Hoek
01/31/11
Reply
  ResuscitationInjections of atropine are used in the treatment of bradycardia (an extremely low heart rate), asystole and pulseless electrical activity (PEA) in cardiac arrest. This works because the main action of the vagus nerve of the parasympathetic system on the heart is to decrease heart rate. Atropine blocks this action and, therefore, may speed up the heart rate. However, in the latest guidelines released by the American Heart association, atropine is no longer routinely indicated as a primary treatment modality in asystole and PEA.[2] The usual dosage of atropine in bradyasystolic arrest is 0.5 to 1 mg IV push every three to five minutes, up to a maximum dose of 0.04 mg/kg. For symptomatic bradycardia, the usual dosage is 0.5 to 1 mg IV push, may repeat every 3 to 5 minutes up to a maximum dose of 3 mg.[3]

Atropine is also useful in treating second-degree heart block Mobitz Type 1 (Wenckebach block), and also third-degree heart block with a high Purkinje or AV-nodal escape rhythm. It is usually not effective in second-degree heart block Mobitz type 2, and in third-degree heart block with a low Purkinje or ventricular escape rhythm. Atropine is contraindicated in ischemia-induced conduction block, because the drug increases oxygen demand of the AV nodal tissue, thereby aggravating ischemia and the resulting heart block.

One of the main actions of the parasympathetic nervous system is to stimulate the M2 muscarinic receptor in the heart, but atropine inhibits this action.

[edit] Secretions and bronchoconstrictionAtropine's actions on the parasympathetic nervous system inhibits salivary, sweat, and mucus glands. This can be useful in treating hyperhidrosis, and can prevent the death rattle of dying patients. Even though atropine has not been officially indicated for either of these purposes by the FDA, it has been used by physicians for these purposes.[4]

[edit] Treatment for organophosphate poisoningAtropine is not an actual antidote for organophosphate poisoning. However, by blocking the action of acetylcholine at muscarinic receptors, atropine also serves as a treatment for poisoning by organophosphate insecticides and nerve gases, such as Tabun (GA), Sarin (GB), Soman (GD) and VX. Troops that are likely to be attacked with chemical weapons often carry autoinjectors with atropine and obidoxime, which can be quickly injected into the thigh. Atropine is often used in conjunction with Pralidoxime chloride.

Atropine is given as a treatment for SLUDGE (Salivation, Lacrimation, Urination, Diaphoresis, Gastrointestinal motility, Emesis) symptoms caused by organophosphate poisoning. Another mnemonic is DUMBBELSS, which stands for Diarrhea, Urination, Miosis, Bradycardia, Bronchoconstriction, Excitation (as of muscle in the form of fasciculations and CNS), Lacrimation, Salivation, and Sweating (only sympathetic innervation using Musc receptors).

Some of the nerve agents attack and destroy acetylcholinesterase by phosphorylation, so the action of acetylcholine becomes prolonged, pralidoxime (2-PAM) is the cure for organophosphate poisoning because it can cleave this phosphorylation. Atropine can be used to reduce the effect of the poisoning by blocking muscarinic acetylcholine receptors, which would otherwise be overstimulated by excessive acetylcholine accumulation.
Dr.Qutub
02/01/11
atropine sulfate, can i use it as an eyes drop would like to know what kind of eye's problem.?
Maria
05/15/09
Reply
  its a drugs used to dilate pupil. dont use it, unless you are prescribed to and asked to use it by proper professionals. if you want to use it as lubricants, good luck :) not only it stinks, and you wouldnt be able to read for 6 hours or more, as it will paralyze the eye's ability to accommodate.
l2p
05/15/09
When will my eye go back to normal size?
okay so a few weeks ago i got shot in my left eye with a paintball gun and the doctors put me on two drops. the first drop is called prednisolone acetate opthalmic suspension and they had me doing it 3 times a day but now only twice. the second drop atropine sulfate opathlmic solution. i know that the atropine drops make your eye dilated. i used to do it 2 times a day then the doctors put me down to 1 and now i dont use it at all.

i wanna know when my eye will go back to normal size because i have been walking around for like a month with two different size eyes and i was really looking forward to my eyes being the same sizes and im scared that it will never go back to normal size.

its been about 36 hours or so since i stopped taking the atropine drops but i am still taking the prednisolone 2 times a day.


also check out this picture of after i got shot lol
http://c4.ac-images.myspacecdn.com/images02/139/l_8dcc60c062674ee7aa7a19523d8d1fd7.jpg
Regina Sakas
06/22/10
Reply
  depending on your eye color (lighter eyes last dilated longer, darker eyes dont last as long) 3-5 days after last instillation.

plus if there's damage to your iris it may never come back down.
princeidoc
06/22/10
How long until the Atropine wears off and my pupil shrinks?
Had an eye injury...wound up having to use Atropine for about 10 days. Stopped the Atropine 4 days ago. I can tell my pupil is shrinking but just slightly. I still have some wacky vision.

How long until everything goes back to normal?

Thanks!! :)
Millie
03/14/10
Reply
  Effefct of Atropine lasts for 7-8 days.
Ashwin P
03/14/10
I'm not so good at research. Could somebody out there be kind enough to look this up for me?
First off, if you answered my earlier question, thanks.

Now, can anyone tell me if "Diphenoxylate HCI & Atropine Sulfate" is/are the same thing as "Lomotil" they're meds.

Thanks for the answers! You have NO IDEA how much I appreciate it.
Traverser
09/27/09
Reply
  Lomotil is a brand name for the combination you posted.
It is an opioid antidiarrheal drug
Tink
09/27/09
What is the nebulizer dose for Atropine?
Trying to find the dosage for Atropine for a SVN. Thanks
Haha, I was more thinking of a regular hospital visit
Missy
04/22/07
Reply
  For bronchospasm the inhaled dose is 0.03 - 0.05 mg/kg/dose 3 -4 times/day. Maximum 2.5 mg
Harmony
04/22/07
Does anyone know a optician practitioner in Sydney, Australia who uses atropine drops to treat myopia?
i am 15 years old and have high myopia and i am hoping to use atropine to retard my prescription from getting worse
Micho L
06/07/08
Reply
  I am in the US, and here, opticians only deal with glasses, and do not handle medications. Optometrists could give you atropine, provided the benefits of this pharmaceutical vision therapy outweigh the risks. At present, studies are underway to assess the validity of the hypothesis. You would not want to endanger your future vision while trying to avoid future vision problems. "Out of the frying pan and into the fire."
Susan S
06/08/08
Does anyone know anything about the eyedrop called Atropine?
Would like to know more about the eye drop Atropine because my experience with it was less desirable and wonder if anyone else has ever had an experience with it? I welcome your feed back Thank, You
Jane M.
01/30/11
Reply
  Ah, atropine, one of mankind's oldest drugs, derived from nightshade and named for one of the three Greek Fates, Atropos, who chose how we each would die. Used in the eye to dilate the pupil, which can be very painful if you are in bright light afterward, and some folks take longer than others to clear it from their system. Used to treat some forms of glaucoma, should never be used in others. Surprisingly in some instances it is a drug of abuse, although a less pleasant selection would be hard to imagine.

http://en.wikipedia.org/wiki/Atropine#Side-effects_and_overdose
fusepark
01/30/11
What sort of a settlement should you ask for when the pharmacy blinds you for 2 weeks with the wrong drug?
My doctor gave me a prescription for pilocarpine which had to be filled at a specialty pharmacy that does titrations.Though the prescription was typed, the pharmacist got the drug mixed up with atropine sulfate (a pupil dialating drug which also paralyzes the muscles that help the eye to focus). Also, the instructions on the bottle were for the pilocarpine, so I ended up getting a dosage that was 50 times the usual dosage for atropine. While nothing terrible happened, the dialation ruined my near vision and forced me to wear dark sunglasses indoors for about two weeks. I was still able to go to work (I am a grad student) but I did so with a huge glare-induced migrane and had to find rides since I was unable to drive. Now the pharmacy's insurance company has been calling me asking about a settlement and I have no idea what to say. The damage was not permanent so suing seems mean. On the other hand, I was in pain for 2 weeks so I should ask for something. Any idea what would be fair?
anonymous
08/13/07
Reply
  Speak to a lawyer, NOW!
DO NOT try to take care of this on your own. Yes...you are entitiled to some type of renumeration. What if it had been filled with something that DID blind you! What if they are filling other scripts wrong, not just yours? An investigation of the pharmacy also seems in order. Just because you escaped unscathed as far as the rest of your life goes....(but, you never know what may happen down the line...it could have done damage you are not aware of that will rear it's ugly head later in life)...they still made a blunder that could have cost you your sight....or your life.
It's not mean....and your lawyer most likely can settle with them without going to court.
I was in a bad auto accident some years ago. We got a small but fair (at the time) settlement without going to court (other drivers fault...)...however, now, 15 years later, my teeth are experiencing problems (my mouth hit the steering wheel) due to that accident (cracks under the fillings I had at the time are causing my teeth to break away in the back)...and I wish now, I had done more at the time.
Cover YOURSELF...do all you can to make sure this doesn't happen to someone else...I understand you not wanting to be be mean and all that....BUT...you have to look out for YOUR best interests right now...cause no one else is going to do it FOR you....
Toots
08/13/07
How long the effect of pupil dilatation lasts in patients who have used the Atropine eye drops?
My months old son had a check up at the eye clinic 4 days ago due to strabismus. The doctors there prescribed 1 drop each eye of Atropine the evening before the appointment and a last one 1.5 hrs before. His pupils are still very dilated. Do you know if this is normal? I haven`t been able to contact his eye doctor yet. Please give me an answer ASAP, I haven't found anything in the web.
anavalj
12/12/08
Reply
  Pupil dilation can last up to two weeks with atropine, but is somewhat dependent on the color of your child's eyes and the strength of the atropine drop prescribed. It also depends on how much of the drop you got into your child's eyes (not a very easy thing to do sometimes)

People with darker colored eyes have more pigment, which absorbs some of the atropine, and causes less atropine to get into the eye to actually dilate the pupil. Dilation effects last longer in people with light blue eyes.

Hope you can get a hold of his eye doctor. It might help to keep him out of direct sunlight (ie wear a hat) as his eyes are probably still light sensitive. The light won't damage his eyes but he may be more comfortable keeping them closed or in the shade.
parrot_gurl
12/12/08
Atropine has the effect of dilating the pupil: does this increase night sensitivity?
Atropine eye drops can dilate the pupil, that much I know. I've read that side effects include light sensitivity, which wouldn't be a good thing in daytime, but might not be so detrimental at night. Also, I've read unconfirmed reports that the effect was used to boost night vision in WWII.

So, how well does it work, if used in conjunction with other methods (vitamin-A supplements, etc.)?
SandyCaesar
01/04/09
Reply
  When a 1 per cent. aqueous solution of atropine sulphate is dropped in a man's eye, the pupil dilates in about fifteen or twenty minutes, but takes two hours more to reach the maximum dilatation. There is no effect on the other eye. If atropine is injected into an excised mammal eye, the pupil dilates, and if an animal is atropinized, stimulation of the third nerve, either central or peripheral to the ciliary ganglia, is without effect on the pupil. The action is, therefore, a purely peripheral one. But it is not a direct effect upon the muscle, for in the atropinized animal direct stimulation of the circular muscle results in contraction; therefore the site of the paralyzing action of the drug must be confined to the third-nerve endings or the neuromuscular junction.

The dilatation from atropine is, therefore, the result of the unopposed action of the radial muscles. It is, however, frequently strong enough to break weak adhesions between cornea and iris, or to make an iris which is strongly attached at two points bow out between the points of attachment. The pupil gradually regains its power, but is not fully restored to normal for one or two weeks. That there is no stimulation of the radial mechanism is evident, for, after atropine, stimulation of the cervical sympathetic results in a still greater dilatation.

A drug which causes dilatation of the pupil is called a mydriatic. Belladonna gets its name from this mydriatic action (bella, beautiful; donna, lady), which makes the eye seem bright and sparkling
Human-Species
01/05/09
How long will it take for the Atropine to wear off and my pupils to shrink back to normal size?
I had an eye injury that required me to use Atropine drops for about 10 days. The drops were d/c'd this past Thursday.

How long will it take for my pupil to shrink back to its normal size?
Millie
03/13/10
Reply
  maybe about 3 days? read the Atropine box. It should tell you the details.
luminous
03/14/10
Has anyone had the atropine/scopolamine injections from the stop smoking clinic?
My husband just had the atropine/scopolamine injections by Dr. Gugga. The purpose is to stop smoking. He is now on Belladona, he still has a scopolamine patch, and he has a new Rx for ativan prn. The side effects of these drugs can cause blurred vision, hallucinations, drowsiness. The Dr said he would be ok to work by day 2 which was Wednesday, but he has been acting very loopy. Has anyone had this injection? Did it make you somewhat tired, or did you not remember the events of the day? I had to get my parents to watch our kids while I go to work, because I don't think he would wake up for them. Does anyone have any experience with this?
Thanks
Beth V
05/12/07
Reply
  Is this a legitimate clinic?? Did you google these drugs to see what they really do? Atropine dilates your eyes and speeds up your heart; belladonna is a poison; ativan is an anti-anxiety drug; and the CIA used to use scopolamine (a depressant) when they interrogated suspects. A small overdose of any ONE of these drugs can be fatal. This sounds like a very dangerous combination. How on earth are they supposed to help you quit smoking? I doubt seriously that any of them should be prescribed for that purpose. Have you spoken to your regular doctor about this?
Alice K
05/12/07
Why cant you use morphine sulfate to treat surgical pain?
I had a herniated disc in my L5S1 area of my back. The doctor gave me morphine sulfate for the pain. Last week I had decompression surgery to correct the problem. I was given a different pain med. that works very well but the doctor told me not to use the morphine for pain. I was given morphine in the hospital but I cant use the morphine sulfate for pain at home. The literature they give with medication when you get a perscription filled even says not to use morphine sulfate to treat postsurgery pain. I just want to know if there is a medical reason why you cant use morphine sulfate to treat surgical pain.
pam s
08/28/07
Reply
  Couldn't say it any better than Matador89 did. He is spot on. I had the same surgery and believe me you won't need the Morphine, that surgery was a blessing for me, I hope it is for you. Good Luck
DeltaQueen
08/28/07
Can morphine sulfate be IV'd through the arm?
Just wondering can someone crush up morphine sulfate and shoot it up? Or does it not work in water? Its Morphine Sulfate not regular morphine. I found needles in my brothers room next to this bottle of morphine sulfates. Please let me know
Jessler
06/20/09
Reply
  Yes you can. If you think your brother is doing this please tell someone. It is very dangerous, he could kill himself with an overdose.
susan
06/20/09
Dosage info of zinc sulfate supplements?
My dermatologist prescribed zinc sulfate supplements for acne.
She just said take them an hour after meals. Each tablet weighs 200 mg.

I'm seventeen years old, medium build. How much am i suppose to take? how many times a day ? What are the dangers of taking high doses?

Does zinc sulfate really help in clearing up skin?
otter
08/18/09
Reply
  Yes, zinc is good for clearing up the skin. My question is, isn't all of the dosage info on the bottle you got? It should tell you how many times a day and how many pills at a time. If you are still confused after looking at the bottle or info that came with the bottle (all prescriptions come with information on dosage and side effects) then please call your doctor.
Huckleberry Sin
08/18/09
Ferrous Sulfate supplement - Is one that says, "Equivalent" to 325mg as good as one that actually is 325mg?
Doctor ordered me to take ferrous sulfate, 325mg, because of very low iron levels in my blood test. In researching which product to buy, I see some that say they HAVE 325mg of ferrous sulfate, and some that say they have (for example) "65mg Iron, Equivalent to 325mg ferrous sulfate.

Is there really a difference between the two, and is one better than the other for iron therapy?

Thanks!
Don P
11/21/09
Reply
  Ferrous sulfate is an extremely oxidative form of iron, meaning it causes cell death when ingested. Many children die each year mistaking the tablets for candy. It's fairly harmless in adults but it does still cause cell damage especially to the liver if taken in high doses or for too long. Ferrous fumarate is a much safer and more tolerable form of iron to take but it can be harder to find. Your doc may be able to find it for you on his computer if you can't.

All minerals have to be bound or chelated to something for it to reach our cells. In this case iron is attached to a sulfate molecule 325mg in total, but the actual iron content (also known as elemental amount) is 65mg. Both the products you mention have the same amount of elemental iron in them. Hope this helps.
mz_dazed
11/21/09
Can I take Methadone with Morphine Sulfate?
My doctor prescribed I take Methadone with Morphine Sulfate to treat my intense lower back pain. I was originally taking Methadone with Roxycodone but today she replaced it with Morphine Sulfate. My pharmacist seemed kinda concerned about me taking those two together. Is it safe to take?
Zorua
08/28/07
Reply
  Your pharmacist is right to be concerned, but I'm sure it is because of the strength of meds, in other words he/she is probably worried that you will be to "high".
You were probably prescribed 10mg methadone tabs, if so it is common. Reason being both methadone and Morphine sulfate are opiates, that means they work through the spinal cord to alleviate pain.
You are absolutely right to check and double check your meds. All I can tell you is that it was eventually prescibed to me this way and I really do have better pain relief now.
Of course everyone reacts differantly to differant medications and in my case we have been working to find a good pain solution for quite a while. Chronic Back Pain is so difficult to treat (pain wise) because levels of pain vary so much that the doctors really must track our communication with them as well as our physical condition, so be sure if you are uncomfortable to contact his office asap.
Good Luck to you, I hope you find the pain relief that you need.
DeltaQueen
08/28/07
Triple Antibiotic Ointment?
Bacitracin Zinc
Neomycin sulfate
Polymyxin B sulfate
Is there any Anti-fungle component here?
JAMES
07/30/06
Reply
  NO....anti-bacterial only and normally for skin infections. Antifungals are things like Tinactin or al ot of other over the counter types for jock itch, female vaginal infections, yeast infections.
Sassy OLD Broad
07/30/06
Do you know any toothpaste that doesnt have sodium lauryl sulfate in it?
Sodium lauryl sulfate is an ingredient present in all toothpaste. It seems that is very harmful for our gum and teeth since it is a detergent.. It seems that it is like high fructose corn syrup that is present in so many kind of food and it is the culprit of obseity. Well now it is sodium lauryl sulfate in toothpaste that it seems to be the enemy in the fight against cavities and gum recession.
jennie
07/17/08
Reply
  I have a tube of Crest cavity protection on the active ingredient it says sodium floride & floride ion it doesn't say it contains sodium lauryl sulfate. hope this helps
Lyn- mom and nana.
07/17/08
im pregnant and taking ferrous sulfate and of coarse prenatal vitamins and metronidazole?
im 12 weeks and my doc prescribed this to me im only taking ferrous sulfate acid and in 2 weeks i take the anti biotic for my vaginal infection, what are the side effects to the anti biotic? and what is ferrous sulfate ?
lovely.
06/10/10
Reply
Is a body wash with Sodium Laureth Sulfate better than a body wash with Ammonium Laureth Sulfate?
Some leading body washes contain Sodium Lauryl Sulfate and Sodium Laureth Sulfate, but others contain Ammonium Lauryl Sulfate and Ammonium Laureth Sulfate. The difference between SLS and ALS isn't really notable, but is there a difference between the body washes?
Fumiko S
01/11/07
Reply
  so my husbands not the only one to read the back of those bottles while he's pooing
jenny
01/11/07
What is the specific gravity of the copper sulfate solution they test blood for anemia with?
Like when you go to a blood drive and they have to test you for anemia, I know they use a copper sulfate solution. But does anyone know the ratio of copper sulfate to water they use? (well I'm assuming it's just those two chemicals)
Donna The Crazy Kid
06/20/09
Reply
  The specific gravity is 2.28 (hydrated) 3.6 (anhydrous).
RAM
06/24/09
Has anyone taking morphine sulfate or Avinza 30mg cp24?
I have servere lower back pain that is shooting down my legs. My doctor put me on this morphine sulfate and I wanted to if anyone has taken this and what side effects you had.
Sweet T
07/23/07
Reply
  I take morphin sulfate three times a day, and i have gotten that shootinig cramping pain in my left leg. It is very painful. The opiats can cause cramping while taking them. try drinking plenty of fluids and streching your leg, it helped for me.
ronnie8905
07/24/07
Can you mix Dextroamphamine and Morphine Sulfate?
I took Dextroamphetamine yesterday at about 1am. Is it ok if I use the Morphine Sulfate injection tonight, or is it too soon to take it?
Mamabear
07/05/09
Reply
  You need to consult the prescribing doctor(s) and the dispensing pharmacist(s).

Why did you take an stimulant at 1am?
crimsonshedemon
07/05/09
Is it okay to take Ferrous Sulfate while taking Vitamin E?
I usually take Myra E and I know that my blood pressure is 90/50. I want to take ferrous sulfate
Janice
03/29/11
Reply
  I think it might be ok to take it with vitamin E. Check here. This site lists many of the foods and supplements that interfere with the body's absorption of iron.

http://truestarhealth.com/Notes/2870003.html
pelican
03/29/11
Is it okay to take Ferrous Sulfate while taking Vitamin E?
I usually take Myra E and I know that my blood pressure is 90/50. I want to take ferrous sulfate

03/29/11
Reply
  I think it might be ok to take it with vitamin E. Check here. This site lists many of the foods and supplements that interfere with the body's absorption of iron.

http://truestarhealth.com/Notes/2870003.html
pelican
03/29/11
what solution works best for recovering undistorted prtozoan cysts and nematode larvae from fecal samples?
need it for my college test............heres the choices i have
glucose, sodium chloride, sodium sulfate, zinc sulfate
Shorty
03/06/07
Reply
  I am just guessing here, but here's the logic: need sodium chloride to make sure there is an osmotic balance in the solution and the organism; and glucose to increase the density of the solution so the organisms float to the top. I have no idea if this is correct.
formerly_bob
03/06/07
how do you use magnesium sulfate ?
My mom hands really hurts. its been hurting for a while already. So she bought Magnesium Sulfate U.S.P. & She wants to know how to use it. How do you use it ???
Daisy
08/28/10
Reply
  http://search.yahoo.com/search?p=magnesium+sulfate+for+healing&ei=UTF-8&fr=moz2-ytff-grpj
Einstein
08/28/10

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MalcolmsStudy: Precipitation is two solids getting together to form an insoluble solid. E.g. Barium nitrate+ sodium sulfate= barium sulfate+sodium sulfate
PunchlineRLSH: @DarkPhoenixRLSH You could look into the oldschool chemicals like curare or atropine
PunchlineRLSH: @DarkPhoenixRLSH If you get the concentration just right, you could use atropine eye-drops as temporary nightvision.
Liesrunsprints: @gatorgirl277 paramedics put in 2 rounds (ephenephrine and atropine) via the port in his leg
Diego_E85: I worked on a pt that coded. Chest compressions, atropine, epinepherine, and she still didn't make it...
christeljulia: RT @TeamMichael777: While Paramedics were trying to give Michael EPINEPHRINE AND ATROPINE. to kick start his heart,via an IV. CM son of a bitch pulled it out